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Characters
- Thing 47 Ben Grimm, better known as the Thing, is the original quintessential tough-guy of the Marvel Universe. But, because of his transformation, he's also the tragic member of the Fantastic Four. Ben was an ace test-pilot until exposure to intense cosmic radiation mutated him into a rock-skinned monster with immense superhuman strength. Ben's exterior is much harder than stone which gives him a rather gruff disposition; but deep down, he has a heart of gold.
- Human Torch 46 The second most powerful member of the Fantastic Four and the younger brother of Sue Richards. Due to an accident caused by cosmic radiation in space, he can manipulate fire, turn his entire body into it and fly. While Johnny is known for his impetuous and sometimes reckless nature, he is also a loyal friend and fearless hero.
- Mr. Fantastic 45 Reed Richards, also known as Mr. Fantastic, is the leader of the Fantastic Four. He can stretch his body to great distances due to his exposure to cosmic rays while in space. He is also considered to be one of the smartest men alive, using his brain to explore alternate dimensions and save the world alongside his family from science-based threats.
- Invisible Woman 44 Susan Storm is a founding member of the Fantastic Four and later the Future Foundation. She is able to create invisible force fields of any shape she conceives and able to turn herself and anything she's in contact with invisible. Sue is the wife of Reed Richards and the mother of their children, Franklin and Valeria.
- Valeria Richards 37 Valeria is the daughter of Sue and Reed Richards and sister to Franklin Richards.
- Franklin Richards 37 Franklin is the son of Reed Richards and Sue Storm, also known as Mr. Fantastic and Invisible Woman of the Fantastic Four. Franklin is an Omega-level mutant with reality-warping abilities; even at a young age he is one of the most powerful beings in the Universe.
- Alicia Masters 37 A blind sculptor and friend of the Fantastic Four. She is married to Ben Grimm, the Thing, and is also the stepdaughter of the supervillain Puppet Master.
- Sky 24 Spyrican mutate gifted with feathered wings and a sonic scream, Sky was a member of the Unparalleled on the planet Spyre. She accompanied Johnny Storm when the Fantastic Four returned to Earth.
- N'kalla 23 N'kalla was a child gladiator made to represent the Skrulls in a mock Kree-Skrull War that was saved by the Fantastic Four and eventually adopted by Ben and Alicia Grimm
- Jo-Venn 23 Jo-Venn was a child gladiator force to represent the Kree in a mock Kree-Skrull War by The Profiteer, he was eventually saved by the Fantastic Four.
- Doctor Doom 19 The very mention of his name makes lesser men tremble! The brilliant scientist whose iron mask conceals his scarred (but once handsome) face! Master of science and sorcery, Victor Von Doom is the monarch of Latveria, attempting the betterment of humanity through world conquest! Unequaled and unrivaled in every manner, Doctor Doom has had many conflicts with both earthly and cosmic super-beings, but he will always be known as the eternal nemesis of Reed Richards and his accursed Fantastic Four!
- Dragon Man 12 Dragon Man is a synthetic lifeform and occasional enemy of The Avengers. He is currently a member of the Future Foundation.
- She-Hulk 12 After being shot by mobsters, Jennifer Walter received a life-saving blood transfusion from her cousin Bruce Banner, aka The Hulk. Due to Banner's irradiated blood, Jennifer gained the ability to transform into the Sensational She-Hulk. She is a recurring member of the Avengers.
- Citadel 11 Spyrican mutate with the ability to increase his size and strength, Citadel is a member of The Unparalleled on the planet Spyre.
- Bentley 23 11 Bentley 23 is a clone of the Wizard who was liberated from his "father" by the Fantastic Four. He rebels against his evil bloodline as a member of the Future Foundation.
- Spider-Man 11 Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
- Victorious 10 A Doom loyalist and citizen of Latveria who convinced Dr. Doom to return as leader of Latveria. In recognition of her loyalty, she was made the Herald of Doom. She is also Dr. Doom's ex-fiancee.
- Wyatt Wingfoot 9 An ally to the Fantastic Four, Wyatt has saved the team on several occasions and shared many adventures with them.
- Sidearm 9 Spyrican mutate with metamorphic molecular control of his own body, Sidearm is the leader of The Unparalleled on the planet Spyre.
- Galactus 8 Galactus is the infamous "Devourer of Worlds" in the Marvel Universe. His powers are nearly omnipotent. He has appointed several entities as his Heralds, imbuing them with the Power Cosmic. He uses energy from the core of planets and universal sources to sustain himself.
- Wolverine 8 A long-lived mutant with the rage of a beast and the soul of a Samurai, James "Logan" Howlett's once mysterious past is filled with blood, war, and betrayal. Possessing an accelerated healing factor, keenly enhanced senses, and bone claws in each hand (along with his skeleton) that are coated in adamantium; Wolverine is, without question, the ultimate weapon.
- Kaylo 7 Spyrican mutate with the power to harness solar energy, Kaylo is a member of The Unparalleled on the planet Spyre. She is married to fellow teammate, Kor.
- Scrum 7 Scrum is the leader of the Monster Mob on Spyre
- Overseer 7 Spiritual leader of the planet Spyre who was bombarded by cosmic radiation, losing his eyes but gaining telepathy. He believed a prophecy that stated the Fantastic Four would bring chaos to Spyre.
- Griever at the End of All Things 7 A being which describes itself as entropy, heat and death. She appears at the end of all things, and has crossed paths with the Fantastic Four and Scarlet Witch.
- Belter 7 A Spyrican mutate with the power of geokinesis, Belter is a member of The Unparalleled on the planet Spyre.
- Kor 7 Spyrican mutate with the power to harness solar energy, Kor is a member of the Unparalleled on the planet Spyre. She is married to fellow teammate, Kaylo.
- Silver Surfer 6 Norrin Radd of Zenn-La is the mighty herald of Galactus, the devourer of worlds. Gifted with the Power Cosmic and a trusty board that's faster than lightspeed, which he can summon at will whenever needed, Norrin Radd travels to distant reaches throughout the universe as the Silver Surfer.
- H.E.R.B.I.E. 6 Originally a replacement for the Human Torch in the 1978 Fantastic Four animated series. H.E.R.B.I.E. often provided comic relief with interactions with the Thing. He has since become an indispensable part of the Fantastic Four in the comics.
- Crystal 6 Crystal is a member of the Inhumans and the younger sister of Medusa, Queen of the Inhumans. She has the power to manipulate the four classical elements of Air, Fire, Water and Earth.
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